Toothpaste is a paste used with toothbrushes to clean and maintain the aesthetics and health of teeth. It not only helps in removing dental plaque but also come to bring various health effect including tooth whitening, reducing bleeding gums, and antibacterial. As people pay more attention to the safety of toothpaste, wanting to use it with natural ingredients.

Recently, Toothpaste manufacturers add some Chinese herbal medicine composition in dental cream, with the effective prevention and treatment of various oral diseases and its low side effects, environmental protection, high-security features and times under the favor of people, this kind of product on the market demand is growing.

Gotu Kola Extract is believed as an effective additive in toothpaste for its healing properties, Gotu kola has been shown to stimulate blood vessel growth in connective tissue, stimulate wound healing, and act as a powerful anti-inflammatory

Modern research found Centella extract has strong central inhibition, anesthesia, and analgesic effect. Can promote the body collagen synthesis and angiogenesis and other important roles, so it is conducive to wound healing; Centroside in centroids extract can also affect the ultrastructure of fibroblasts, increase the amount of DNA synthesis of fibroblasts, promote the proliferation of fibroblasts, and promote the synthesis of collagen in fibroblasts in a dose-dependent manner.