Product Name Taxus Extract Paclitaxel Powder
Alias Name Taxol
Active Ingredient Paclitaxel
Specification 99%
Cas No. 33069-62-4
Molecular Formula C47H51NO14
Molecular Weight 853.9 g/mol
Appearance White powder
Part Used Taxus bark
Origin Jiangsu, China
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What is Paclitaxel?

Paclitaxel is a natural diterpene alkaloid with white crystalline powder, extracted from the bark of the gymnosperms Taxus Chinensis, and well known for its strong antineoplastic and anti-cancer activities.

Using the solubility of paclitaxel, the isolation process for obtaining paclitaxel involves organic solvent soaking, Column chromatography, and recrystallization. Finally, got the paclitaxel powder with purity of more than 99 percent.

Paclitaxel and Health benefits:

Paclitaxel is a natural anticancer drug and clinically used to treat breast cancer, ovarian cancer, lung cancer and other cancer. It is the first chemical drug isolated from the natural herb, that approved by FDA. Let’s show more info on the efficacy and effects of paclitaxel.

Paclitaxel and anticancer effect:

Taxol, as a tetracyclic diterpene compound with anticancer activity, was firstly isolated from Taxus in 1971, and have been found it may help human against cancer by inhibiting the growth of cancer cell. In addition, Scientists have continuing to study its unique and profound properties for an anticancer agent.

Microtubules, polymers of tubulin that form part of the cytoskeleton and provide structure and shape to eukaryotic cells, are closely related to making up the mitotic spindle fibers necessary for M phase cell division. For rapidly dividing tumor cells, paclitaxel inhibits the mitotic spindle, thus stopping tumor cells in G1 and M stages until death.

Application:

Paclitaxel as an anticancer agent, it most widely used in anticancer drugs, and has been used for the treatment of various cancer including breast cancer, ovarian cancer, cervical cancer, lung cancer, and AIDS-related Kaposi sarcoma.

References:

https://www.cancerresearchuk.org/about-cancer/cancer-in-general/treatment/cancer-drugs/drugs/paclitaxel

https://www.macmillan.org.uk/cancer-information-and-support/treatments-and-drugs/paclitaxel

https://pubchem.ncbi.nlm.nih.gov/compound/paclitaxel

https://en.wikipedia.org/wiki/Paclitaxel

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695897/